Addison's Disease Is Basically an Research Paper

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Treatment of Addison's disease involves addressing the hormone deficiency using "replacement dose." [NIH] The drugs that are used as replacements for cortisol functions are known as glucocorticoids. Hydrocortisone or Dexamethasone or Prednisone is the drugs of choice. Since blood levels of Hydrocortisone can be directly measured it is an excellent choice for treatment and it makes drug dosage adjustment very easy. [Sarah Baker] Patients with Aldosterone deficiency are treated with fludrocortisone (Florinef). Inside the human body the secretion of cortisol is affected by stress. More cortisol is secreted during stress, fever, vomiting, etc. Therefore during periods of stress or physical ailments patients may require additional dosages of cortisol therapy. During sick days it is therefore necessary to consult with the physician, as a higher dose of cortisol therapy is essential. "Sick day rules" are different from normal days for glucocortisoid treatment dosage.

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Also, if the patient suffers from severe vomiting that would make the tablet form of cortisol therapy ineffective it is necessary to immediately administer cortisol in the form of injections. (Injectible glucocorticoid) [NIH]

Addison's disease patients should do regular physical activities that reduce stress. Also regular meditation that helps reduce stress is strongly advocated by many physicians. [Mark Rosenberg, M.D.] Patients with Addison's disease should always carry a Medic alert tag (a bracelet) that would inform a physician about their condition. This is very important under emergency circumstances as it alerts the physician of the underlying condition enabling him to provide appropriate intervention. Addison's disease can be effectively managed with appropriate dose of hormone replacement medication, dietary changes and by maintaining an active life style. [Sarah Baker].....

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