Pathophysiology of Chronic Venous Insufficiency and Deep Venous Thrombosis
Chronic venous insufficiency (CVI) pathophysiology is either the obstruction or reflux of venous blood flow (Gujja, Wiley, & Krishnan, 2014). The perforating veins valve normally functions by preventing the reflux of blood from the deep veins into the superficial veins. CVI occurs when there is venous hypertension that is caused by incompetent valves. Venous blood will escape from its normal antegrade flow path and it refluxes backward into the veins of an already congested leg. After prolonged standing, the individual's veins will be completely filled and the venous valves will be flat open. This results in a high hydrostatic venous pressure due to the unbroken column of fluid that is extending from the head to the foot. The failed valves will cause the column of standing blood in the vein to remain high even during ambulation. Hydrostatic pressure will increase during and immediately after ambulation, which results in venous congestion.
Deep venous thrombosis (DVT) occurs when there are two of the Virchow's triad present in a patient. The triad consists of venous stasis, vessel wall injury, and altered blood coagulation (Prandoni et al., 2015).
Stuck Writing Your "Comparing Chronic Venous Insufficiency and Deep Venous Thrombosis" Essay?
This triad will cause inflammation of the vein walls, which would eventually lead to thrombus formation. In response to the inflammation, venous thrombi are attached to the vein wall and they contain tail like attachment made of white blood cells, red blood cells, and fibrin. It is possible for the tail to grow or spread in the direction of blood flow as the layers of clot are formed over time. This is critical since some of the blood clots might break off, travel in the blood stream and they end up blocking other veins.
Venous thrombosis is the formation of a blood clot in a vein. While arterial thrombosis is the development of a blood clot in an artery.
Impact of Smoking on The Pathophysiology of CVI and DVT
A smoker is more likely to suffer from DVT since smoking will make the blood cells stickier than they normally should and this results in them attaching to other blood cells resulting in clots. Smoking also alters fibrinolysis and this leads to blood clots not being destroyed normally. This increases the formation of blood….....
Cepero, S. M. (2018). Ozone Therapy in leg ulcers of patients with chronic venous insufficiency. Journal of Ozone Therapy, 2(2).
Gujja, K., Wiley, J., & Krishnan, P. (2014). Chronic Venous Insufficiency. Interventional cardiology clinics, 3(4), 593-605.
Katseni, K. K., Dimakakos, E., Bramis, K., Saatsakis, G., & Katsenis, K. (2017). The effect of MPFF on skin temperature at different stages of chronic venous insufficiency. Hellenic Journal of Surgery, 89(5-6), 203-212.
Prandoni, P., Lensing, A. W., Prins, M. H., Pesavento, R., Piccioli, A., Sartori, M. T., . . . Noventa, F. (2015). The impact of residual thrombosis on the long-term outcome of patients with deep venous thrombosis treated with conventional anticoagulation. Paper presented at the Seminars in thrombosis and hemostasis.
Swanson, E. (2015). Ultrasound screening for deep venous thrombosis detection: a prospective evaluation of 200 plastic surgery outpatients. Plastic and Reconstructive Surgery Global Open, 3(3).
"Comparing Chronic Venous Insufficiency And Deep Venous Thrombosis" (2018, March 24) Retrieved May 14, 2025, from https://www.aceyourpaper.com/essays/comparing-chronic-venous-insufficiency-deep-venous-thrombosis-essay
Latest MLA Format (8th edition)
Copy Reference
"Comparing Chronic Venous Insufficiency And Deep Venous Thrombosis" 24 March 2018. Web.14 May. 2025. < https://www.aceyourpaper.com/essays/comparing-chronic-venous-insufficiency-deep-venous-thrombosis-essay>
Latest Chicago Format (16th edition)
Copy Reference
"Comparing Chronic Venous Insufficiency And Deep Venous Thrombosis", 24 March 2018, Accessed.14 May. 2025, https://www.aceyourpaper.com/essays/comparing-chronic-venous-insufficiency-deep-venous-thrombosis-essay
