Gout Rakieh, C & Conaghan, P. (2011). Article Review

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Gout

Rakieh, C & Conaghan, P. (2011). Diagnosis and treatment of gout in primary care.

The Practitioner, 255 (1746):17-20

Gout, once called the 'rich man's disease,' is the most common form of inflammatory arthritis in men over the age of 40. Risk increases with age and an estimated 7% of men aged over 65 and 3% of women aged over 85 have gout. It is caused by the deposition of monosodium urate (MSU) crystals in the joints as a consequence of raised serum uric acid levels. But while increased uric acid clearly poses an additional risk, hyperuricaemia is more common than full-fledged gout, indicating other risk factors are significant.

The risk of gout is associated with high levels of alcohol consumption.

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Consumption of large amounts of red meat (and other purine-rich foods like seafood) is also associated with gout, while dairy products and coffee are protective. Approximately 1-2% of the population has gout, an unsurprising statistic given its association with poor diet and the fact that diets high in alcohol and red meat are more common in the developed world. Metabolic syndrome (obesity with insulin resistance) is also strongly associated with gout. Certain medications such as diuretics can contribute to gout. Gout can only be diagnosed conclusively by analyzing the affected joints for MSU crystals in the synovial fluid. Inflamed and painful joints are one of the primary….....

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