Invasive Aspergillosis Essay

Open, View, and/or
Download this Document

Total Length: 397 words ( 1 double-spaced pages)

Total Sources: 3

Invasive Aspergillosis: How Immunosuppression May Lead to Contraction

1. Explain why you think the patient presented the symptoms described.

The patient developed fever, cough, chest pain, and hemoptysis because invasive aspergillosis typically begins in the lungs before spreading to other organs via the bloodstream. Once Aspergillus has infiltrated the lungs (airborne pathogenic mold), the epithelial cells within the respiratory system are triggered, and inflammatory mediators such as cytokines are released. Cytokines then recruit polymorphonuclear leukocytes, and its infiltration causes fever (Cadena, Thompson, & Patterson, 2016). Therefore fever (chief complaint) demonstrates the actions of the inflammatory response, which is the second line of defense after innate immunity (McCance & Huether, 2019).

2. Identify the genes that may be associated with the development of the disease.

The following six genes are associated with the development of invasive aspergillosis: 1) NF?B1, 2) NF?B2, 3) RelA, 4) RelB, 5) REL, and 6) IRF4 (Lupianez et al., 2016).

Stuck Writing Your "Invasive Aspergillosis" Essay?

View All Our Example Invasive Aspergillosis Essay

Have A Custom Example Essay Written

Nuclear factor kappa-light-chain enhance of activated B cells (NF?B) is a protein complex that regulates the immune response to infections. It is held in the cytoplasm but moves to the nucleus once pathogens infiltrate a cell, tissue, or an organ. NF?B is made up of NF?B1 and NF?B2, which bound to either RelA, RelB, or REL. The IRF4 gene belongs to the interferon regulatory factor (IRF) family. It activates interferons in response to infections caused by viruses (Lupianez et al.,

3. Explain the process of immunosuppression and the effect it has on body systems.

Immunosuppression refers to the decreased capacity or efficacy of the immune system (McCance & Huether, 2019). It is caused by auto-immune diseases such as rheumatoid arthritis, Crohn’s disease, or systematic lupus erythematosus. Additionally, it can be induced by medications, radiation therapy, or surgery (splenectomy). Overall, immunosuppression increases the severity of infections and neoplastic diseases because the immune system.....

     Open the full completed essay and source list


OR

     Order a one-of-a-kind custom essay on this topic


sample essay writing service

Cite This Resource:

Latest APA Format (6th edition)

Copy Reference
"Invasive Aspergillosis" (2020, March 08) Retrieved June 27, 2025, from
https://www.aceyourpaper.com/essays/invasive-aspergillosis-2174977

Latest MLA Format (8th edition)

Copy Reference
"Invasive Aspergillosis" 08 March 2020. Web.27 June. 2025. <
https://www.aceyourpaper.com/essays/invasive-aspergillosis-2174977>

Latest Chicago Format (16th edition)

Copy Reference
"Invasive Aspergillosis", 08 March 2020, Accessed.27 June. 2025,
https://www.aceyourpaper.com/essays/invasive-aspergillosis-2174977
   

Open, View, and/or
Download this Document
order custom essay example