Meconium Aspiration Syndrome (Mas) Primarily Term Paper

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How many enzymes from the liver and pancreas are actually present will vary somewhat with gestational age and there is no actual way to know which one of the many chemicals produces the severe inflammatory response that is seen in even mild cases of MAS. It is thought, however, that bile salts are mainly responsible for this problem. When biopsies are taken, they reveal both macrophage infiltration and polymorphonuclear cell infiltration. Soon, alveolar edema occurs, along with the formation of hyaline membranes. It is possible that the surfactant may be inactivated, but it can also be secreted, and pulmonary hemorrhaging may also occur. Some research samples have also shown the presence of microthrombi located in the pulmonary vasculature, as well as a more pronounced muscularization and thickness of the distal arterioles in the lungs (pedsccm.wustl.edu, n.d.).

Where medical care and treatment is concerned, prevention is very important. Monitoring fetal status and paying close attention to problems is something that all obstetricians should be aware of. However, if prevention is not possible, there are some things that can be done in the way of treatment for MAS. There are medications that can be given to these infants to help them recover the pulmonary function that they might otherwise lose with MAS.

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Surfactant replacement is also important. These tiny patients should also be checked out for potential cardiac problems and if there is pulmonary hypertension present, that should be treated as well. When steps are taken to help these newborns, almost all of them will recover all of their pulmonary function completely and have no lasting problems from the MAS that they had at birth. There is a higher infection chance in their first year, however, so they must be cared for carefully by parents and others that watch over them (www.emedicine.com,2004).

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