Nano Artery the Use of Research Paper

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2010; Chorny et al. 2010). This research is still quite new, however, and the question remains as to whether or not nanoparticles can truly serve as a replacement for stents by prohibiting plaque growth through a variety of means, including more targeted and longer-range delivery of pharmaceutical substances that destroy such build-ups and inhibit plaque deposits from forming. The efficacy of this approach has already been preliminarily demonstrated, but the long-term viability and safety of this intervention method as well as attendant risks have not yet been fully determined (Chan et al. 2010; Chorny et al. 2010).

IV. Motivation for Research

Despite the numerous advancements that have been made in treating plaque build-up in arteries and the general treatment and control of other cardiac issues, coronary artery disease is still the leading cause of death in North America and is a significant problem in other parts of the world, as well (Schoenhagen & Nissen 2003). This provides ample motivation for the study of techniques that might be more effective in treating and preventing coronary artery disease than those that are currently employed; the benefits of such research will directly impact the lives of many individuals by providing increasingly effective, less invasive, and more cost-effective treatments that prolong life and improve the quality of life. There are also more intrinsic motivations for conducting this research, including the ability to develop knowledge and work at the forefront of medical and engineering science, and though personal these motivations are not to be taken lightly.

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V. Improvement of Quantitative Approaches

Current assessment methods for this technology generally involve focusing on minute details of the functionality of the nanoparticles without long-term data gathering and statistical analysis efforts taking place (Chan et al. 2010; Chorny et al. 2010). It is the goal of this research to improve these methods by including not only the functionality of the newly developed technologies, but also to assess the health improvements and/or rates of re-incidence in patients that undergo nanoparticle treatment, with regression analysis used to determine the degree of correlation between this treatment and changes in health. This will also allow for direct comparison to other treatment methods in terms of efficacy......

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