Proton Pump Inhibitors Mechanisms Applications Cellular Effe Essay

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Proton Pump Inhibitors


Proton Pump Inhibitors


Discuss the symptoms for which PPIs are prescribed and the intended target of these drugs.
Typically, the stomach produces acid to kill bacteria (germs) and help digest food by activating certain enzymes. However, the acid is corrosive; therefore, the body has to develop mucous to act as a natural barrier that protects the stomach lining from being eroded. Nevertheless, some individuals have broken mucous enabling the acid to pass through and damage the stomach causing ulcers (Mullin et al. 2009). That may come up with symptoms like a burning pain in the upper abdomen, temporal pain whenever one eats anything, bloating, heartburn, vomit, and dark stool in severe instances.
In other people, there could be a problem with the Sphincter, which usually keeps the stomach tightly closed. Hence, it could result in acid escape into the gullet, causing acid reflux with signs like throat inflammation and heartburn.
Subsequently, the admission of Proton Pump inhibitors would stop the lining cells from secreting more acid. The reduction of acid production can prevent the formation of ulcers and assist in the healing process (Mullin et al., 2009). Moreover, decreasing the amount of acid secreted will minimize the symptoms associated with acid reflux like heartburn. The way that the inhibitors for the Proton Pump work is that they inhibit the enzyme composed of the hydrogen-potassium and the adenosine triphosphatase composition system in the stomach lining cells. It is responsible for the production of stomach acid.
An organelle that would also be affected by these drugs.

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