Science Daily Called: Pepper Component Article Critique

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The introduction of Capsaicin to mice that have prostrate cancer will cause many of the cancer cells to die."

According to a team of researchers from the Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center, in collaboration with colleagues from UCLA, the pepper component caused human prostate cancer cells to undergo programmed cell death or apoptosis (http://www.sciencedaily.com/releases/2006/03/060319150754.htm)."

When the Capsaicin was introduced to mice that had prostrate cancer growing it killed approximately 80% of the cancer cells.

This was done by leading the capsaicin to follow molecular pathways that lead to the apoptosis of those cells.

Prostate cancer tumors treated with capsaicin were about one-fifth the size of tumors in non-treated mice. Capsaicin had a profound anti-proliferative effect on human prostate cancer cells in culture," said Sren Lehmann, M.D., Ph.D., visiting scientist at the Cedars-Sinai Medical Center and the UCLA School of Medicine. "It also dramatically slowed the development of prostate tumors formed by those human cell lines grown in mouse models (http://www.sciencedaily.com/releases/2006/03/060319150754.htm)."

The dose of the element fed to the mice was equivalent to400 milligrams being given to a 200 pound man on a three times a week basis according to the researchers.

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This equals between three and eight fresh habanera peppers each week.

The conclusion that can be drawn from this study is that the use of Capsaicin on human prostrate patients in 400 milligrams per week should reduce cancer growth significantly.

While there was no discussion in the article about planning a future study, the article provides enough evidence of the fact that Capsaicin may be extremely beneficial in the future treatment of prostrate cancer it will be important to design and conduct a study using human prostrate patients as participants.

Because of the large number of cancer cells the substance killed, this is something that needs to be explored with human participants as soon as possible.

The article provides a clear overview of the experiment and results and allows the reader to understand the significance of the consequences without creating a bias about those results.

REFERENCE (http://www.sciencedaily.com/releases/2006/03/060319150754.htm)

Pepper Component Hot Enough to Trigger Suicide in Prostate Cancer Cells. Science Daily......

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