Thiamine Vitamin B1 Metabolism Functions Deficiency Essay

Open, View, and/or
Download this Document

Total Length: 678 words ( 2 double-spaced pages)

Total Sources: 3

Page 1 of 2


Thiamine Metabolism


Thiamine is a water-soluble vitamin, Vitamin B1, and serves as a cofactor for enzymes with Mitochondrial localization. Since it is not endogenously synthesized, the available dietary sources of thiamine are beef, poultry, nuts, cereals, and nuts. It plays a critical function in oxidative and nonoxidative carbohydrate metabolism in the energy transformation process. Other functions of thiamine are the antioxidation effect on neurotrophins, which oppresses oxidative stress-induced activation that plays a critical role in activating the immune system, signaling and maintenance in cells, and cell uptake mechanisms.1 Intestinal enzyme phosphate Hydrolyzes thiamine into a free form absorbed in the small intestines. The Phosphorylated is stored in the heart, kidneys, brain, and liver. Thiamine has a half-life of 1 to 12 hours and can be stored in the body between 14 to 18 days. Consequently, regular dietary intake is necessary to avoid the development of a deficiency.
The recommended thiamine intake differs with age and gender but a standard intake of 1.2mg/day among men and 1.1mg/day for women with increments to 1.4 mg/day for pregnancy and lactation, respectively.3. Regular intake is imperative to maintain the correct thiamine levels in the body. The intestinal uptake of thiamine is regulated by a molecular mechanism that involves thiamine transporters-1 and -2, which are products of Solute Carrier Family 19 Member 2…

[…… parts of this paper are missing, click here to view the entire document ]

…a decarboxylating component of alpha-ketoglutarate dehydrogenase.

Stuck Writing Your "Thiamine Vitamin B1 Metabolism Functions Deficiency" Essay?

View All Our Example Thiamine Vitamin B1 Metabolism Functions Deficiency Essay

Have A Custom Example Essay Written

3 Thiamine triphosphate appears in the neurophysiological function localized in the cell membrane structure. Thiamine triphosphate (TTP) acts as an activator of chloride channels with high conductance. As established, thiamine deficiency results in various disorders, such as Korsakoff’s Syndrome, Alzheimer’s Disease (AD), diabetes mellites, depression, and Polyneuropathy, that affect cell physiology or cognitive functions.
Thiamine can be administered orally, intramuscularly, or intravenously. The administration is useful in treating congestive heart failure, Alzheimer’s disease, and cataracts. The administration of thiamine orally is not recommended since it is not adequate for symptomatic patients. Intravenous administration is considered the best option since the administration of 100mg thiamine….....

Show More ⇣

     Open the full completed essay and source list


OR

     Order a one-of-a-kind custom essay on this topic


sample essay writing service

Cite This Resource:

Latest APA Format (6th edition)

Copy Reference
"Thiamine Vitamin B1 Metabolism Functions Deficiency" (2022, January 22) Retrieved June 6, 2026, from
https://www.aceyourpaper.com/essays/thiamine-vitamin-b1-metabolism-functions-2182739

Latest MLA Format (8th edition)

Copy Reference
"Thiamine Vitamin B1 Metabolism Functions Deficiency" 22 January 2022. Web.6 June. 2026. <
https://www.aceyourpaper.com/essays/thiamine-vitamin-b1-metabolism-functions-2182739>

Latest Chicago Format (16th edition)

Copy Reference
"Thiamine Vitamin B1 Metabolism Functions Deficiency", 22 January 2022, Accessed.6 June. 2026,
https://www.aceyourpaper.com/essays/thiamine-vitamin-b1-metabolism-functions-2182739
   

Open, View, and/or
Download this Document
order custom essay example